IVF
What does IVF mean?
IVF is a treatment for a variety of fertility problems that involves combining an egg and sperm outside the body in a special lab. The fertilized egg (embryo) is allowed to grow in a protected environment for a few days before being transferred to the woman's uterus. This increases the chances of pregnancy.
IVF can help with many fertility problems and offers many couples the best chance of becoming pregnant.
Step by step IVF process
Your treatment will be coordinated by your fertility specialist, who will have the support of an experienced team of nurses, counsellors, and embryologists. We understand how important a family having is to you. You can be assured that we will provide you with the highest standard of fertility care.
Here is what you can expect to happen when going through IVF.
Step 1: Initial specialist appointment
At your first appointment, your Fertility Specialist will review your medical history, carry out the following tests and start to advise you about your treatment options.
- Blood tests: These include antenatal screening, anti-Mullerian hormone (AMH), hormone profile (pituitary, ovarian and thyroid) and karyotype (chromosome - genetic material - check) to make sure you have the right number of chromosomes and that they are in the right order.
- Pelvic ultrasound: To get an idea of the structure of the pelvis, the uterus and how it looks, the ovaries and how they are positioned, and if there are any problems that need further investigation.
- Semen analysis: If your male partner is present, he'll have a semen analysis to make sure there are enough good quality sperm. They will look at the shape, size, number, and movement of the sperm.
Step 2: Consultation prior to treatment
After your initial appointment, you'll usually see your fertility specialist again for a follow-up appointment to discuss your results. Your doctor will use these results to help decide what's best for you and how best to proceed.
Your doctor will give you the medication you need, explain the treatment cycle and show you how to administer your own FSH (follicle stimulating hormone) injections. We recommend that both you and your partner attend this appointment.
Step 3: Start of the treatment
There are several types of ovarian stimulation for IVF treatment. The most used protocol is the antagonist protocol, the timing of which is explained in more detail below.
The first day of IVF treatment is the first day of your menstrual cycle. As soon as you start your period, you'll need to call the nurses to let them know about it. Hormone stimulation will usually start on day 2.
Step 4: Hormone stimulation
You will give yourself these injections using a diabetic pen. The aim is to stimulate your ovaries to produce more eggs than usual. You will return to your clinic after five days to see how your body has responded to the injections. This is to avoid under- or over-stimulating your ovaries. The more eggs we can retrieve, the more likely we are to achieve fertilizations and a pregnancy.
Step 5: Monitoring treatment
If you're doing well with your FSH injections, you'll have a follow-up scan and blood test to check that your body is going in the right direction (stimulated) for your IVF cycle. This will also help us to determine the most appropriate time to collect the eggs. All your blood tests and ultrasound scans will be carried out by your doctor at our clinic. They are included in the cost of your treatment.
Step 6: Trigger injection
As soon as you have the optimal number and size of follicles, we will schedule you for egg retrieval. You'll be given a trigger injection of hCG (human chorionic gonadotropin) in the evening. The egg retrieval procedure will take place 36 to 38 hours later. The hCG injection replaces the body's natural luteinizing hormone. It triggers ovulation, so that the eggs mature and are ready for retrieval.
Step 7: Egg collection
Two days later, you'll come in for day surgery to get the eggs retrieved (this is the only day you'll need to take off work during your IVF cycle). The procedure takes about 20-30 minutes. You will be fully asleep while your fertility doctor uses a thin needle through the wall of your vagina to retrieve the follicles, guided by an ultrasound. You will be told the number of eggs retrieved when you have recovered from the procedure.
Step 8: Fertilization of the eggs
Following egg collection, your eggs are immediately taken to the laboratory where they are combined with your partner's sperm and then fertilized. Fertilization will be carried out using Intracytoplasmic Sperm Injection (ICSI). This involves inserting one sperm into each egg.
You will usually receive a call from the laboratory with an update after the eggs and sperm have been tested.
Step 9: Development of the embryo
The next day, embryologist examine the eggs to see if fertilization occurred. We usually grow embryos in the lab up to day 5, known as the blastocyst stage. This is because there is strong evidence that these embryos are more likely to implant in the uterus.
Step 10: Embryo transfer
Embryo transfer is a simple day surgery procedure, usually performed five days after egg retrieval. The highest quality embryo is transferred into the uterus through a very fine catheter inserted through the cervix, a procedure like cervical screening. In some cases, we may recommend an earlier embryo transfer.
Step 11: Pregnancy test
We’ll arrange for you to have a blood test two weeks after the embryo transfer. Occasionally, women can still have a period despite being pregnant, so this blood test will be done even if your period has started. We do not recommend that you use a urine pregnancy test kit. This could give a false result.
We will arrange an ultrasound scan about three weeks later if the pregnancy test is positive.
Are you ready to start your IVF journey?
Start your journey with us by requesting an appointment with our leading fertility specialist. Initial consultations can be face-to-face or online, depending on what works best for you.
Call us on +905550526458 to find out more about getting started or fill in the form below. We are committed to supporting you throughout your journey and can help with any questions you may have.
Frequently Asked Questions About IVF Treatment and Process
IVF stands for In Vitro Fertilization. In vitro means 'in a dish', and fertilization takes place outside the body.
A successful IVF pregnancy is the desired outcome of IVF, which is primarily a treatment for infertility. An egg and sperm are combined outside the body in a specialized laboratory, unlike natural pregnancy. The fertilized egg (embryo) grows in a protected environment for a few days before being transferred to the woman's uterus. This increases the chances of pregnancy.
Briefly, IVF begins by stimulating the ovaries for about two weeks to produce multiple eggs. Once the ovaries have been stimulated to produce these eggs, a fertility doctor will surgically remove the eggs and place them in a dish with sperm. The hope is that the eggs will be fertilized and develop into embryos over a period of five days.
The start of your IVF cycle can vary depending on when your treatment plan is confirmed and when your period starts. From day 1 of your period, each IVF treatment cycle takes approximately four to six weeks. While the length of each IVF step can vary, below is an example of a standard IVF treatment cycle timeline.
Treatment starts on the first day of your period, depending on your individual circumstances. Whether you're using ovulation tracking, IVF or IUI, this is the first day of your cycle and a sign to start treatment.
Gender selection during IVF treatment is not legally permitted in Turkiye due to the ethical, legal, and social issues it raises. In Turkiye, sex selection is only available if it is needed to prevent certain genetic disorders that would only affect one sex. It is not available for family balancing.
IVF patients have 1-2 injections a day on average. The first injection is an FSH injection. FSH stands for Follicle Stimulating Hormone. You will give yourself these injections for the next five days and then return to our clinic to see how your body has responded to the injections. Your doctor will then recommend either increasing or decreasing the number of injections, depending on how your body has responded.
This depends largely on your pain tolerance. Most women do not find IVF treatment painful, and you should never experience extreme pain. However, discomfort from side effects such as abdominal cramping, bloating or breast tenderness can occur at various stages of the IVF process due to injections and hormone fluctuations. Procedures such as egg collection use anesthesia to ensure a painless experience, and over-the-counter medications are recommended to relieve discomfort.
IVF treatment is tailored to your individual needs. One of two main treatment protocols, long down regulation or antagonist treatment cycles will be prescribed for most patients undergoing IVF.
There is a 5-day period when embryos develop into blastocysts during the IVF process. Often the extra embryo(s) can be frozen and stored for use in future cycles if more than one healthy embryo develops during this period.
To find out more about what's involved in IVF treatment, book an appointment with your fertility specialist right now.
Which treatment plan is best for you?
- Pretreatment & consent consultation
- Stimulation of ovaries to develop multiple follicles
- Monitoring ultrasound scans during stimulation
- Egg collection and, sedation for egg collection
- Sperm preparation and fertilization of eggs (ICSI)
- Embryo culture to day 5
- Progesterone test just before embryo transfer
- Fresh embryo transfer
- Freezing and storage of the remaining embryos (if appropriate)
- Review consultation
- Medication
- Transportation
- Hotel accommodation
- Pretreatment & consent consultation
- Stimulation of ovaries to develop multiple follicles
- Monitoring ultrasound scans during stimulation
- Egg collection and, sedation for egg collection
- Sperm preparation and fertilization of eggs (ICSI)
- Embryo culture to day 5
- Progesterone test just before embryo transfer
- Fresh embryo transfer
- Freezing and storage of the remaining embryos (if appropriate)
- Review consultation
- Medication
- Transportation
- Hotel accommodation
- Pretreatment & consent consultation
- Stimulation of ovaries to develop multiple follicles
- Monitoring ultrasound scans during stimulation
- Egg collection and, sedation for egg collection
- Sperm preparation and fertilization of eggs (ICSI)
- Embryo culture to day 5
- Progesterone test just before embryo transfer
- Fresh embryo transfer
- Freezing and storage of the remaining embryos (if appropriate)
- Review consultation
- Medication
- Transportation
- Hotel accommodation